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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TUBA1C
All Species:
54.55
Human Site:
T223
Identified Species:
92.31
UniProt:
Q9BQE3
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BQE3
NP_116093.1
449
49895
T223
N
L
D
I
E
R
P
T
Y
T
N
L
N
R
L
Chimpanzee
Pan troglodytes
Q5R1W4
451
50117
T223
N
L
D
I
E
R
P
T
Y
T
N
L
N
R
L
Rhesus Macaque
Macaca mulatta
XP_001108255
437
48681
D218
D
I
C
R
R
N
L
D
I
E
R
P
T
Y
T
Dog
Lupus familis
XP_850665
449
49891
T223
N
L
D
I
E
R
P
T
Y
T
N
L
N
R
L
Cat
Felis silvestris
Mouse
Mus musculus
P05214
450
49941
T223
N
L
D
I
E
R
P
T
Y
T
N
L
N
R
L
Rat
Rattus norvegicus
Q6AYZ1
449
49919
T223
N
L
D
I
E
R
P
T
Y
T
N
L
N
R
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510837
454
50448
T226
N
L
D
I
E
R
P
T
Y
T
N
L
N
R
L
Chicken
Gallus gallus
P09644
448
49930
T223
N
L
D
I
E
R
P
T
Y
T
N
L
N
R
L
Frog
Xenopus laevis
P08537
449
49861
T223
N
L
D
I
E
R
P
T
Y
T
N
L
N
R
L
Zebra Danio
Brachydanio rerio
NP_919369
449
49935
T223
N
L
D
I
E
R
P
T
Y
T
N
L
N
R
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P06603
450
49890
T223
N
L
D
I
E
R
P
T
Y
T
N
L
N
R
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34690
448
49895
S221
N
L
D
V
E
R
P
S
Y
T
N
L
N
R
I
Sea Urchin
Strong. purpuratus
XP_001178141
451
50085
T223
N
L
D
I
E
R
P
T
Y
T
N
L
N
R
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P14641
451
49713
T223
S
L
D
I
E
R
P
T
Y
T
N
L
N
R
L
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.7
96.4
99.3
N.A.
96.2
99.1
N.A.
97.3
94.4
98.8
98.2
N.A.
96.6
N.A.
87.9
96.2
Protein Similarity:
100
98.8
97.3
100
N.A.
98.4
100
N.A.
98.2
96.6
99.7
99.7
N.A.
98.6
N.A.
95.3
98.8
P-Site Identity:
100
100
0
100
N.A.
100
100
N.A.
100
100
100
100
N.A.
100
N.A.
80
100
P-Site Similarity:
100
100
13.3
100
N.A.
100
100
N.A.
100
100
100
100
N.A.
100
N.A.
100
100
Percent
Protein Identity:
N.A.
84.7
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
94.9
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
93.3
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
100
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
93
0
0
0
0
8
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
93
0
0
0
0
8
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
0
86
0
0
0
0
8
0
0
0
0
0
8
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
93
0
0
0
0
8
0
0
0
0
93
0
0
86
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
86
0
0
0
0
8
0
0
0
0
93
0
93
0
0
% N
% Pro:
0
0
0
0
0
0
93
0
0
0
0
8
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
8
8
93
0
0
0
0
8
0
0
93
0
% R
% Ser:
8
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
86
0
93
0
0
8
0
8
% T
% Val:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
93
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _